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Topiramate (or the brand-name version, Topamax ) is an antiseizure drug thats prescribed off-label for weight loss

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Modern pharmacologic approaches allow the relative contribution of each receptor to be quantitatively tuned, mitigating adverse effects while preserving efficacy ( 5.3 Central neuropeptides and the behavioral dimension of feeding Beyond gut-derived peptides, centrally expressed neuropeptides exert a profound influence over feeding behavior while simultaneously modulating stress, arousal, and reward pathways