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Huang J, Li H, Wang X, Liang X, Zhao T, Hu J, et al
A decade ago, insulin was the standard next step when oral medications failed
The compound is very interesting from a medical point of view, as it has effect to almost all organs in extremely low concentrations (in a range from ng to mg and more per a kilogram of body weight) and without any toxic or side effects
Patients carrying certain FTO (rs9939609) or MC4R (rs17782313) variants may experience different appetite-suppression intensity and gastrointestinal adaptation timelines
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