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This timing leverages physiologic factors including reduced somatostatin inhibition during sleep, increased GHRH receptor sensitivity during evening hours, and optimal metabolic conditions supporting growth hormone synthesis and secretion, while morning or midday administration stimulates smaller daytime pulses with less consistent metabolic benefits

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Dietary Modifications: Balanced Diet: A nutrient-rich diet emphasizing whole, unprocessed foods, including vegetables, lean proteins, and healthy fats, supports metabolic health while minimizing sugar and refined carbohydrates