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Methimazole-induced agranulocytosis in patients with graves disease is more frequent with an initial dose of 30 mg daily than with 15 mg daily

While these findings offer reassurance in cases of inadvertent exposure to GLP-1 medications during the first trimester of pregnancy, larger trials are needed for more conclusive results

This approach is grounded in the understanding that despite sharing a therapeutic class, individual GLP-1 RAs can exhibit diverse biological effects and safety profiles due to their distinct molecular structures and mechanisms of action [1,4,5,6]

Common adverse reactions include nausea, belching, acid reflux with heartburn, diarrhea, vomiting, constipation, abdominal discomfort, fatigue, injection site reactions, and hypersensitivity reactions

John Roxborough, MD , and our team are here to help you understand the differences between these medications and choose the one thats right for you