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In mammalian ovaries, the FOXO1 protein regulates atresia and follicular growth by promoting the induction of apoptosis in OGCs 123

540,541 The depletion of hepatic retinoid stores impairs the initial recovery of liver mass, suggesting a link between retinoid metabolism in HSCs and hepatocyte proliferation

Its functional parts include the recognition arm to selectively bind the target RNA, the catalytic core to employ magnesium ions, and other assisting factors to activate water molecules, which attack and cleave the target phosphodiester bond of the RNA

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