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In clinical trials, retatrutide dosage was slowly increased to improve tolerance

MatsushimaNishiwaki R., Kamoi S., and Kozawa O., Upregulation by Duloxetine of the Transforming Growth FactorInduced Migration of Hepatocellular Carcinoma Cells via Enhancement of the cJun NTerminal Kinase Activity, Cell Biochemistry and Function 41 (2023): 814822

Three diabetes incretin medications are now approved for pediatric use starting at age 10 (see cheat sheet), and two incretin-based weight management medications are approved for children aged 12 and older

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Novo dominated the diabetes space in 2022 thanks to the continuing Ozempic hype