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Thus Compound 1 (containing the highly reactive oxyferryl intermediate shown in equation 2) if not immediately involved in the disproportionation step of Equation 3, can go on to inactivate the enzyme
Discussion GPCR phosphorylation is a crucial PTM involved in the control of cell signalling by regulating receptor desensitisation and internalisation propensities, recruitment of -arrestins, and redirecting receptors towards specific signalling pathways (23)
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Alterations in these proteins have previously been associated with substance use and addiction
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