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Testing may include SAM, SAH, methionine, homocysteine, whole-blood histamine, copper, zinc, ceruloplasmin, urinary pyrroles, organic acids, lactate, pyruvate, glutathione-related markers, 8-OHdG and lipid peroxides when clinically appropriate

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Some prefer taking it in the morning to support the liver's daily functions, while others take it before bed to support the bodys natural repair cycle during sleep