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For reference, the FDA label dose of tesamorelin alone is 2 mg/day (legacy formulation) or 1.28 mg/day for the newer EGRIFTA WR formulation, and ipamorelin has been studied at roughly 100-300 mcg per dose in research settings

Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats

The ~1 mcg/kg Saturation Dose Idea A related community concept is that a GHRP reaches a saturation dose near roughly 1 mcg/kg the notion being that beyond this amount the ghrelin receptor is maximally engaged and additional peptide yields diminishing GH return

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Villares R, Kakabadse D, Juarranz Y, Gomariz RP, Martnez-a C, Mellado M