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The common co-morbidity with obesity, diabetes, and metabolic syndrome makes it almost impossible to distinguish the pathophysiology (100)

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Leeb T, Bruhn O, Philipp U, Kuiper H, Regenhard P, Paul S, Distl O, Chowdhary BP, Kalm E, Looft C: Assignment of the equine S100A7 gene (psoriasin 1) to chromosome 5p12p13 by fluorescence in situ hybridization and radiation hybrid mapping

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Thats why its often considered during: Sports injuries Ligament or tendon strains Post-surgical recovery Some practitioners use it for gut-related concerns since it was originally studied in relation to stomach lining protection