Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs
At the American College of Rheumatology meeting in November 2010 (data available) there were two studies looking at cherry juice
Protein S -glutathionylation is an important post-translation modification, providing protection of protein cysteines from irreversible oxidation and, at the same time, serving to transduce a redox signal by changing structure/function of the target protein
The total human evidence base, as of this writing, consists of the following: 1) a Phase I safety trial of 42 healthy volunteers that was registered in 2015, canceled in 2016, and never published, 2) a retrospective case series of 12 patients with knee pain, no control group, and no validated outcome measure, and 3) a 2025 pilot safety study involving two healthy adults who received intravenous infusions at a single private clinic in Florida
GHK-Cu is a naturally occurring compound known for its regenerative and anti-inflammatory properties, often used to support skin and hair health
