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This study was limited by being an open-label trial design as well as only being 52 weeks long, which is insufficient to assess true long-term diabetes-related and cardiovascular outcomes related to the use of icodec

It also plays an important role in maintaining the intracellular free CoA pool, when excess intra-mitochondrial acyl- groups are present, through the reverse transport of fatty acyl groups as acylcarnitines by the L-carnitine system (Figure 1

Understanding that weight regain is a biological response rather than personal failure is essential for patients and clinicians

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