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260,261 Owing to its rate-limiting enzymatic activity in NAD + salvage pathway, the elevated expression of NAMPT in the innate immune cells, including macrophages and dendritic cells, further proposed a link between intracellular NAD + levels and inflammation

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Curcumin and BDMC may act by inhibiting the downstream Syk pathway, thereby suppressing the activation of MAPK ERK, JNK, and p38, as well as NF-B and translocation of PKC- [70,71,72,73,93]