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Given its essential role in the detoxification of lipid hydroxy peroxides, and its overexpression in most of myeloid malignancies, GPX4 inhibition has emerged as a promising therapeutic strategy to induce ferroptosis as a mean of eradicating myeloid leukemia cells
Chen et al., 2023a
Regulatory Status GHK-Cu is available as a compounded peptide through FDA-regulated compounding pharmacies
Trends Biochem Sci 34(4):200205 Sasaki T, Kitamura T (2010) Roles of FoxO1 and Sirt1 in the central regulation of food intake
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