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Potential Role in Early Type 1 (Autoimmune) Diabetes A few weeks ago Dandong and colleagues published a series of 10 patients with recent diagnosis of autoimmune diabetes (with autoantibody assays), a HbA1c level of 11.7% and fasting C-peptide (reflecting insulin production) of 0.65 ng/ml

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These drugs initially came to market for diabetes and we have since added obesity, sleep apnea and fatty liver to the list of indications and we expect many more formally recognized indications to follow

The FDA label includes a boxed warning about thyroid C-cell tumors observed in rodent studies, though the relevance to humans remains uncertain