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TAK242 (Resatorvid), a selective TLR4 inhibitor, suppresses NFB activation, reduces cytokine releases, and mitigates alveolar damage in models of acute lung injury (157)

Since earlier studies provided signals that febuxostat may increase the risk for cardiovascular events, the Cardiovascular Safety of Febuxostat and Allopurinol in Patients with Gout and Cardiovascular Morbidities (CARES) trial was conducted as a Food and Drug Administration requirement to assess the safety of the drug

doi: 10.1016/j.beem.2015.04.008 71 FauvetRPonceletCHugolDLavaurAFeldmannGDaraE

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