HA, influenza hemagglutinin (n = 3 biological replicates)
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Weeks 13-24: Peak Results Phase The peak results phase sees continued fat loss at slightly reduced rates as the body approaches a new homeostatic set point
Subjects were 50 years of age with established CVD (defined as previous CV, cerebrovascular, or peripheral vascular disease), chronic heart failure (New York Heart Association class II or III), or chronic kidney disease (CKD) of stage 3 or higher, or were 60 years of age with at least one CV risk factor (microalbuminuria or proteinuria, hypertension and left ventricular hypertrophy, left ventricular systolic or diastolic dysfunction or anklebrachial index 65 years), and CV risk profile at baseline on time to first occurrence of MACE, the individual components of MACE (CV death, nonfatal MI, or nonfatal stroke), hospitalization for unstable angina or heart failure, and revascularization
It's possible that AOD9604 may influence the fat cells and lipolytic receptors, particularly given its observed association with changes in weight and fat in murine models