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This limits applicability to non-obese HFpEF phenotypes, e.g., those driven by hypertension or aging without significant adiposity, which may differ in pathophysiology and treatment response

It's a complex picture, and more data is needed to fully understand these potential risks

Using data from the National Health and Nutrition Examination Survey (NHANES III), a study confirmed that American children with overweight were twice as likely to be iron deficient than children with normal weight (11)

PMID: 41807758, DOI: 10.1038/s41569-026-01269-9

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