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As an example, the combination of GLP1RA liraglutide with metformin in infertile obese PCOS patients increased the pregnancy rate after IVF treatment compared to metformin treatment alone although weight loss was similar in these groups, 52 supporting the hypothesis of endometrium as an effective target for GLP1RA therapy

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Since glutathione peroxidase is made of selenium, the enzyme activity will be compromised when selenium is depleted