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November 24, 2023

Beyond its immunomodulatory effects, the interaction of the microbiota with the immune system is now recognized as an important regulator of energy balance, as well as glucose and lipid metabolism, exerting systemic effects on the host (Mederle et al., 2024)

Use of cocaine and other stimulant-like drugs, such as amfetamine, methamfetamine and ecstasy (or 3,4-methylenedioxymethamfetamine [MDMA]), increase glucose production and inhibit glucose clearance, which increases the risk of DKA

Orforglipron (Foundayo) showed an average weight loss of 11%

They both have a boxed warning on their drug labels that indicates a potential risk for thyroid tumors