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Alogliptin (0.01% in diet) combined with exercise training (30 min) for 8 weeks showed benefits in high-fat diet-fed Balb/c and KK/Ta mice

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Together, this multi-layer remodeling across the PFC, NAc, amygdala, and hippocampus provides a mechanistic bridge linking depressive and addictive pathology (Fig

Combining metabolic modulators with immune-regulating therapies represents a promising strategy for improving SLE treatment outcomes