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Key studies assessed glycemic control, weight management, insulin dependence, graft function, and adverse effects

Melanotan II is a synthetic analog of the naturally occurring melanocortin peptide hormone -melanocyte-stimulating hormone

There is no good-quality evidence to suggest that people of different ethnic backgrounds are of greater risk of toxicity at either therapeutic or supra-therapeutic doses

The sphingosine-1-phosphate receptor modulators represent a key class of oral therapies in the treatment of multiple sclerosis, particularly for relapsing forms and active secondary progressive multiple sclerosis