Curdy C, Kalia YN, Guy RH
Compounded options: Compounded Semaglutide Injections (starting at $299/month) Compounded Tirzepatide Injections (starting at $399/month) GLP-1 Liquid Drops GLP-1 Lozenges Oral Semaglutide Liposomal Tablets FDA-approved options: Wegovy Pen (once-weekly injection, starting at $199/month through Shed) Wegovy Pill / Foundayo (once-daily oral tablet, starting at $149/month) Zepbound (via LillyDirect after provider approval) The needle-free formats, including drops, lozenges, and oral tablets, are particularly relevant for people who find injections to be a significant barrier
1 in 2 adults will be obese by 2030 (www.nejm.com) 1 in 4 adults will be severely obese by 2030 (www.nejm.com) Prevalence of diabetes (Type 1 and Type 2) will increase by 54% from 35M people in 2015 to 54M people in 2030 (www.nih.gov) Growth in percentage of population with obesity and severe obesity from 1999-2018: On the Positive Side The American Medical Association has recognized obesity as a "chronic disease" because it can be the underlying cause of other medical conditions, such as heart disease, diabetes, and even some cancers
GLP-1 action in L6 myotubes is via a receptor different from the pancreatic GLP-1 receptor
A Fresh Start for Weight Loss This Spring Quick Summary This guide helps you use the spring season to restart your weight loss with practical, seasonal strategies
