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Their waist size, blood pressure, A1c, and cholesterol all got worse with the regain
GLP-1 receptor agonists, by achieving greater weight loss than obtained with other medications, may represent a therapeutic opportunity for improving obesity in patients with PsO and HS, with resulting decrease in CVR and, in general, improvement in the medium to long term
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As there is no meaningful expression of GLP-1 receptors on hepatocytes, the major effect of GLP-1 agonists on MASH is likely to be indirect and may be related to a reduction in calorie intake, body weight and insulin resistance, all of which would lead to reduced liver lipid accumulation and hepatic inflammation 7,8
Atherosclerosis 220 , 381386 (2012)
a process that highlights the efficiency of the mechanisms of cellular specification (Merkle et al., 2004
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