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doi:10.1111/ijcp.14455 Rist PM, Buring JE, Cook NR, Manson JE, Kurth T

It affects the hands and feet and can have an impact on many bodily processes

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It is believed to help support cell migration and tissue remodeling, both of which play important roles in repairing injured muscles and connective tissues

Consistent with this expanding in vivo landscape, additional tumor contexts are now being reported where FSP1 inhibition alone can restrict tumor growth, including chromophobe renal cell carcinoma, where FSP1 inhibition decreased tumor growth substantially in vivo and synergized with GPX4/SLC7A11 perturbation in vitro 81