Klein, C
Theyre powerful, working on multiple systems, but should be seen as part of long-term condition managementnot a quick fix
Front Microbiol 9:2297
10.3389/fpsyt.2025.1656969 Front
Furthermore, given the aforementioned purported mechanisms for the improving effects of L-carnitine/synbiotics on weight or metabolic parameters, it could be conceived that concomitant supplementation of L-carnitine and synbiotics may confer more pronounced impacts on these indicators, potentially through simultaneous modulation of energy homeostasis (8, 30), increasing fatty acid oxidation (8, 30), reducing adipogenesis or stimulating adipocyte lipolysis (21, 30), alleviating insulin resistance and glucose homeostasis (10, 31, 33), or attenuating systemic inflammation (56, 57), in a complementary or synergistic manner probably mediated through concurrent targeting of metabolic/inflammatory signaling pathways including CPT-Ia (20, 21), PDHC (8, 19), PPAR- (21, 31, 37), AMPK (30, 37), or NF-B (31, 34)