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Allison KC, Chao AM, Bruzas MG, McCuen-Wurst C, Jones E, McAllister C, Gruber K, Berkowitz RI, Wadden TA

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In the STEP 1 trial, dual-energy X-ray absorptiometry (DXA) substudies showed that semaglutide treatment resulted in a greater proportional decrease in fat mass compared to lean body mass over 68 weeks, though absolute lean mass reductions were observed alongside the predominant fat loss