References [1].Floh L, Gnzler WA, Schock HH, Glutathione peroxidase: a selenoenzyme
Applying vitamin C to your skin may reduce hyperpigmentation by interfering with an enzyme called tyrosinase, which is responsible for the production of melanin, a natural skin pigment ( Moreover, vitamin C acts as a brightening agent and can reduce the appearance of darkened spots without changing the natural color of your skin ( Some human studies that combine topical vitamin C with iontophoresis an electrical gradient applied to the skin found significant reductions in hyperpigmentation ( Though this method is promising, iontophoresis increases vitamin C absorption into your skin, meaning that topical application of vitamin C alone may not yield the same results ( Furthermore, most related studies use vitamin C in combination with other anti-hyperpigmentation ingredients like alpha-hydroxy acids, making it hard to determine the specific effects of the vitamin
No PCT is required as 5-Amino-1MQ does not affect hormonal pathways
DNA Cell Biol 23:412418 Wen T, Rothenberg ME (2016) The regulatory function of eosinophils
Farnesol conjugates with reduced glutathione (GSH) forming glutathione S-conjugate (F-GS) concomitant with oxidation of GSH to the disulfide form (GSSG), a reaction catalyzed by GPX