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Accordingly, approved indications expanded in early 2024 to include not only reduction of hyperglycemia, but also weight management in non-diabetic patients, and even cardiovascular risk reduction in patients with elevated weight and comorbid cardiovascular disease
Given how nuanced the impact of GLP-1 analog treatment on depression might be, it is crucial to consider sex as a vital variable and report it and analyze it as such in preclinical as well as clinical studies on this association
Effectiveness, tolerability, approval status, indication, and patient response all matter
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