Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Insulin Glargine as Add-on to Metformin (With or Without Sulfonylureas) in Insulin-Naive Patients With Type 2 Diabetes (SUSTAIN 4): A Randomised, Open-Label, Parallel-Group, Multicentre, Multinational, Phase 3a Trial
[1] [2] This secondary benefit can improve insulin sensitivity over time, further enhancing blood glucose control
Do not try to persuade, says Dr Winnett, but provide safety data and rebound rate research results to help patients make informed decisions. Use the conversation as an opportunity to explain that obesity is a chronic condition, and stopping medication marks a transition, not the end of treatment
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Optimal hydration is essential during semaglutide therapy, both for general health and to mitigate gastrointestinal side effects
