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J Reprod Immunol 163:104251 Fakhr Y, Brindley DN, Hemmings DG (2021) Physiological and pathological functions of sphingolipids in pregnancy

According to the latest guidelines from the American Veterinary Medical Association (50) and guidelines adopted by institutions such as Boston University (51) and the University of Maryland (52), the rats were anesthetized by intraperitoneal injection of ketamine (80 mg/kg) and xylazine (10 mg/kg), in compliance with approved ethical standards (53,54)

[DOI] [PubMed] [Google Scholar] Mason HL, Myers CS, Kendall EC

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Because of these promising results, exendin-(9-39) was granted breakthrough therapy designation for the treatment of congenital hyperinsulinism by the Food and Drug Administration, and studies to evaluate efficacy and safety of multiple dose regimens are under development (36)