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1,5 Importantly, this patients weight loss was likely multifactorial (diet, exercise, semaglutide) as was the improvement in bilateral optic disc edema (weight loss, acetazolamide, semaglutide)

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This enhanced weight loss effect stems from its dual mechanism: by mimicking both GLP-1 and GIP hormones, Tirzepatide may improve insulin sensitivity and appetite regulation more efficiently than GLP-1 alone