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We report that IFN- skews antigen presentation in favor of HLA-B-restricted peptides, including both conventional and alternative antigens, which are recognized by islet-infiltrating CD8 + T cells of T1D patients

This confirms that the N-terminal modification confers the intended enzymatic stability and validates the pharmacokinetic rationale for the structural design

Carbon monoxide rescues ischemic lungs by interrupting MAPK-driven expression of early growth response 1 gene and its downstream target genes

Repeat to desired dosage or as directed by a healthcare professional