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41 In patients with overweight or obesity without diabetes, the SURMOUNT-1 trial showed that tirzepatide 15 mg weekly led to a mean body weight reduction of 20.9% after 72 weeks of treatment, compared with 3.1% with placebo

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Lemas, PhD, assistant professor in the department of health outcomes and biomedical informatics, and faculty member at the Institute for Child Health Policy at University of Florida College of Medicine, said the FDA currently recommends that women stop using GLP-1s at least 2 months before conception due to fetal toxicity that was observed in some animal studies

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