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Activation of downstream signaling: The binding of Dihexa to c-Met receptor activates downstream signaling pathways, including the mitogen-activated protein kinase (MAPK) pathway and the phosphoinositide 3-kinase (PI3K) pathway

In another study that examined the molecular mechanisms behind the effects of liraglutide on oxidized low-density lipoprotein in endothelial cells [68], liraglutide was found to suppress LDL-induced immune cell adhesion to the endothelial cells by inhibiting the expression of vascular adhesion molecules including E-selectin and VCAM-1 both of which have been related to the development of atherosclerosis [68,69,70,71] (refer to Figure one)

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