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Once-weekly injection is convenient for many users

There is no human titration schedule, no human pharmacokinetic study, no human safety margin, and no FDA-approved label

When you swallow a B12 pill, several steps have to work for it to be absorbed: stomach acid and the enzyme pepsin must release B12 from food or the supplement, the stomach must secrete a protein called intrinsic factor that binds to B12, and the B12-intrinsic factor complex must reach the ileum (the end of the small intestine) where it is finally absorbed

As the gas interacts with lipids, it may trigger mild oxidative stress