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J Phys Chem A 121(28):52455256
Mutations applied to the key residues Phe260 (gatekeeper), Asn240 (1 st activity controller) and Leu244 (2 nd activity controller) led to significant differences in the substrate preference of the enzyme
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DPP-4 inhibitors (also known as gliptins), oral medications which modestly increase endogenous incretin levels and have no impact on cardiovascular outcomes or body weight
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