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MASLD and metabolic dysfunctionassociated steatohepatitis (MASH), the histologic phenotype of MASLD characterised by liver injury and inflammation in addition to steatosis, is a major public health issue as it increases the risk of liverrelated complications, such as cirrhosis and hepatocellular carcinoma, while also increasing the rates of fatal and nonfatal cardiovascular events, chronic kidney disease, T2D, extrahepatic cancers [1] and severe bacterial and nonbacterial infections [2]

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Glutathione is widely known as the master antioxidant because of its central role in protecting cells from oxidative stress