Chronic high blood sugar levels initiate a cascade of metabolic abnormalities, which ultimately induce oxidative stress and inflammation, exacerbating nerve injury through excessive production of reactive oxygen species (ROS) and promoting neuronal apoptosis
Since the pKa of Sec is ~ 5.2, the selenol (RSeH) of Sec exits in selenolate (RSe ) form under the physiological condition [8, 11,12,13,14,15,16,17,18]
Use it alongside a nourishing balm to keep lips soft and prevent dryness
However, your health care provider might consider alternatives such as Wegovy, Mounjaro, or Saxenda, all of which are GLP-1 medications but not all are FDA-approved for weight loss specifically.
Crit Rev Biotechnol 10:205222 Kera Y, Kiriyama T, Komura S (1985) Conjugation of acetaldehyde with cysteinylglycine, the first metabolite in glutathione breakdown by gamma-glutamyltranspeptidase