The TrialNet Natural History Study of the development of type 1 diabetes: objectives, design, and initial results
GLP-1 medications are a powerful tool, not a magic bullet
Monitor urine color as a hydration indicatorpale yellow suggests adequate hydration, while dark yellow or amber indicates the need for more fluids Increase fluid intake during episodes of nausea, vomiting, or diarrhea to compensate for losses and prevent dehydration Sip water throughout the day rather than consuming large volumes at once, which may worsen nausea Consider oral rehydration solutions (available over-the-counter) if experiencing persistent diarrhea or vomiting, as these replace both fluids and electrolytes Moderate caffeine intake , as it can have mild diuretic effects, though regular caffeine consumers typically develop tolerance to this effect Patients experiencing persistent nausea may find it challenging to maintain fluid intake
These were landmark numbers that established tirzepatide as the most effective approved weight loss medication at the time of its launch
However, when you decide to stop taking them, Wolver said, the cravings will come rushing back