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Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD

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Mechanism of Action Sermorelin exerts its effects through high-affinity binding to and activation of growth hormone-releasing hormone receptors (GHRHR) expressed on somatotroph cells in the anterior pituitary gland

Model-informed dosing and TDM utilizing a Bayesian-based platform provides a significant advantage over conventional guidelines for the achievement of goal cAUC exposure