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Red Flag Symptoms Requiring Urgent Assessment Contact your GP urgently, call NHS 111, or attend A&E if you experience: Severe, persistent abdominal pain , particularly if sharp, constant, or worseningthis may indicate pancreatitis, a rare but serious adverse effect of GLP-1 receptor agonists

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For lean individuals with isolated visceral fat accumulation, Tesamorelin alone may be sufficient

Muscle tissue burns more calories at rest than fat tissue, so losing muscle while losing weight creates a compounding problem