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As a clinical context point, peptides such as BPC-157 and ipamorelin are not FDA-approved drugs, and access through compounding pharmacies has narrowed

Peer review Peer review information Communications Biology thanks Gregory Barshtein and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Stress Stress, both physical and psychological, induces the release of ACTH and cortisol, particularly via CRH and AVP (183,184), and increases the turnover of these neurohypophysiotropic factors by increasing the transcription of CRH and AVP (185)

The relevant mechanisms and implications will be described in detail below (Figure 3)

When used intentionally, peptides can help restore not just sexual functionbut a renewed sense of connection to the body and self