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The interplay between -synuclein pathology, neuroinflammation, dysfunction of mitochondria, oxidative stress, and altered protein degradation pathways culminates in neuronal degeneration

The volume of BAC water added decides the final concentration in mg/mL, which in turn decides the syringe draw volume for any target dose

however, its pathogenesis remains unclear

Since MTX, one of the DMARDs used in clinical practice, showed no obvious influences on the differentiation of osteoclasts (Supplementary Fig

Amongst people with HF, up to 50% are estimated to have type 2 diabetes and, vice versa, around 20% of the over 500 million people living with type 2 diabetes have been shown to have comorbid HF (ClinicalTrials.gov IDs NCT04916470 and NCT04788511), it may be relevant to consider obesity-related HFpEF as a specific (sub)phenotype, whether coexisting with type 2 diabetes or not