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Understanding why these FDA-approved GLP-1 receptor agonists may not work as expected requires examining multiple factorsfrom medication dosing and administration technique to underlying medical conditions and lifestyle behaviors

And individuals using GLP-1 for reasons beyond weight loss, such as metabolic health optimization or inflammatory conditions, may not need full therapeutic doses

If you are taking tirzepatide and do not want to become pregnant, talk with your OB/GYN about reliable contraception

GLP-1 RA therapies are also preferred to insulin in people with T2D who need further glucose lowering than can be obtained with oral agents [64]