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Once contaminated by bacteria, their efficacy may decline at best, and severe infections may occur at worst

A 2021 peer-reviewed review of NNMT in obesity and type 2 diabetes states explicitly that 'clinical trials targeting NNMT have not been reported' meaning every quantitative efficacy figure available for this compound comes from mice, and there is currently zero published human efficacy data

Sam Rhee: Agreed

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It is commonly used as a skin conditioning agent and is appreciated for enhancing the overall sensory and visual quality of products