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In the animal model, GCs administration decreased the mRNA expression of preproglucagon, the precursor of GLP-1 (10, 11)

Taken together, these patterns suggest that GLP-1 adoption is not only transforming diabetes and obesity care but also influencing prescribing behavior and patient management across a broader set of comorbid markets

Few adults under age 50 report having taken these drugs to treat chronic conditions, but similar shares of 1829-year-olds (7%) and 3049-year-olds (6%) report having taken them for weight loss

A large 2023 study including people without diabetes who were using GLP-1 agonists for weight loss found that this class of medications may increase the risk of gastrointestinal conditions, such as gastroparesis

This helps with weight loss