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Insurance coverage may vary, and the price may be significantly higher or lower depending on what your insurance will pay for

The conversion guidance that exists for transitioning between other GLP-1 agonists can provide some framework for thinking about dosing during transitions, though no specific tirzepatide-to-retatrutide conversion protocol has been established in clinical literature

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[See Warnings and Precautions (5.1).] In the event of overdose with JANUMET XR, contact the Poison Control Center

Starting with smaller, more frequent meals and staying hydrated before your first dose helps