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The limiting dilution sphere formation assay showed that the cells that were treated 20 days earlier with the combination of sertraline and 6 Gy irradiation were intrinsically rewired and presented a decreased sphere formation efficiency, indicating a 3-fold reduction and loss of long-term self-renewal capacity ( p = 0.0061) (Fig

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The proportions of M1M6 and [ 3 H]BPC157 in plasma radioactive components at different sampling times demonstrated that [ 3 H]BPC157 was the main plasma component at 0.05 h (3 min) after administration and was subsequently degraded into small molecular peptide fragments in the following 0.167 h (10 min) (Figure 5A)

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