The researchers confirmed that while both lean and fat mass are reduced during treatment, the reduction in fat mass is more substantial, resulting in an overall favorable change in body composition
N Engl J Med 2008;358:25452559
However, during increased electron flux, superoxide production may reach a critical threshold, which may allow trafficking of superoxide anions through the mitochondrial transition pore into the cytosol, in which further damage and/or the activation of additional ROS sources may occur
With my husband, I was able to explain my fatigue away as exhaustion from a long shift at work (Im a NICU nurse)
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